Booken N, Schumann T, Fuchslocher M, Goerdt S, Goebeler M [Successful therapy of discoid lupus erythematosus with efalizumab.] [JOURNAL ARTICLE] Hautarzt 2009 May 14.
The therapy of discoid lupus erythematosus (DLE) is occasionally a therapeutic challenge. Topical treatment is often not sufficient and therapy with antimalarials [(hydroxy-) chloroquine] not always successful. We report on a 50-year-old male patient with recalcitrant chronic DLE who experienced within 12 weeks at first improvement and then almost complete remission for 11 months after off-label application of the anti-CD11a antibody efalizumab.
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